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The effects of CTX- p -QM-1h-NLC on the expressions of TrxR, Bax <t>and</t> <t>Caspase-3</t> in tumors of 4T1 tumor-bearing Balb/c mice. ( A ) Representative target protein bands. The experiment was performed at least in triplicate. ( B ) Relative ratio of TrxR. ( C ) Relative ratio of Bax. ( D ) Relative ratio of Caspase-3. The grayscale quantitative analyses of the expressions of TrxR, Bax and Caspase-3 were performed using the ImageJ software (1.53e). Error bars represent mean ± SD. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared with the model group.
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The effects of CTX- p -QM-1h-NLC on the expressions of TrxR, Bax and Caspase-3 in tumors of 4T1 tumor-bearing Balb/c mice. ( A ) Representative target protein bands. The experiment was performed at least in triplicate. ( B ) Relative ratio of TrxR. ( C ) Relative ratio of Bax. ( D ) Relative ratio of Caspase-3. The grayscale quantitative analyses of the expressions of TrxR, Bax and Caspase-3 were performed using the ImageJ software (1.53e). Error bars represent mean ± SD. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared with the model group.

Journal: International Journal of Molecular Sciences

Article Title: Enhanced Anti-Tumor Activity of Cetuximab-Modified Nanostructured Lipid Carriers Loaded with Para -Quinone Methide Derivative p -QM-1h

doi: 10.3390/ijms27083674

Figure Lengend Snippet: The effects of CTX- p -QM-1h-NLC on the expressions of TrxR, Bax and Caspase-3 in tumors of 4T1 tumor-bearing Balb/c mice. ( A ) Representative target protein bands. The experiment was performed at least in triplicate. ( B ) Relative ratio of TrxR. ( C ) Relative ratio of Bax. ( D ) Relative ratio of Caspase-3. The grayscale quantitative analyses of the expressions of TrxR, Bax and Caspase-3 were performed using the ImageJ software (1.53e). Error bars represent mean ± SD. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared with the model group.

Article Snippet: The primary antibodies used in the experiments were as follows: TrxR (bs-8299R, Bioss, Beijing, China), Bax (bsm-52316R, Bioss, Beijing, China), Caspase-3 (bsm-61071R, Bioss, Beijing, China) and β-actin (GB15003, Servicebio, Wuhan, China).

Techniques: Software